Friday, May 11, 2012

Three Major Themes

The three major themes that connect various topics in this course are amino acids and proteins, nucleic acids, and glycolysis.
Nucleic acids are major topic of this course.  Our body is made up of many complex processes, molecules, structures which code for specific functions. Nucleic acids are the material that makes up part of the DNA. From previous knowledge it was understood how nucleic acids pair with eachother, but in this class the over all structure made it more clear. How the nucleic acids are attached to the backbone and the strcture of the whole nucleotide was very interesting. The structure of DNA made more sense after understanding nucleic acids and nucleotides. The over all structure of DNA is important to understand because it is the instruction manual for the cells in the body.
(Google)

Amino acids and proteins are another major topic in this course. There are 20 common amino acids which make up proteins in the process of translation. The body needs the right amino acid in order to make a specific protein. Amino acids and proteins are one form of how genetic information is expressed in order to perform specific tasks. For example, amino acids code for a protein that is needed to catalyze a reaction in our cells. In this course, greater knowledge is gained of how important every little detail is to our cells. The understanding of what makes up a protein helps connect why a protein might be denatured and how that denaturation causes diseases.

(Google)


Glycolysis is the third major topic that was covered in this class. Glycolysis is the first step in the process of making ATP. It provides the cell with the energy to perform specific tasks that are needed in the body. The information in this class made it clear how efficient the body is in making and using energy.

 (Google)

           

Thursday, May 10, 2012

How would you explain the connection between glucose entering the body and energy created by the body to a friend, using your new biochemistry knowledge.

Carbohydrates are a major food source which energy is derived from. One type of carbohydrates is glucose. When glucose enters our body it undergoes a metabolic pathway called glycolysis, which means breaking glucose apart. Glycolysis is the process that your cells undergoe to breakdown glucose and make energy. One molecule of glucose is broken down at a time which produces two molecules of pyruvic acid. Many oxidation reactions occur during this process and the energy released is used to form ATP. The initial step involves two phosphates which attach to glucose. Then the glucose with a phosphate at each end splits into two three carbon molecules. Then each of the three carbon molecules undergoes through multiple steps to convert into pyruvate. During this step electrons are transferred to the coenzyme NAD+ to form NADH and ATP is formed. In aerobic conditions the pyruvate is oxidized further to make more ATP and under anaerobic conditions the pyruvate is converted into lactic acid. There is 4 ATP’s produced in glycolysis, but only a net gain of 2 ATP’s.

                                   First step in Glycolysis
                                                       (Google)

Second Step in Glycolysis
                                                                           (Google)